BioProcess TEA

BioProcess TEA Calculator

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Chemical Inputs

Name:

C:

H:

O:

N:
Financial Inputs

Target Selling Price: $/kg

MSP Margin: %

Payback Period: Years

Discount Rate: %

Tax Rate: %

% Debt Financed: %

Debt Interest Rate: %

Loan Term: Years
Plant Level Inputs

Capacity: kta

Annual Uptime: %

Batches "On Spec": %

200 500 1,000
Main Fermenter Size: x1000L
Raw Materials

Glucose: $ /lb

Ammonia: $ /lb

Natural Gas: $ /MMBtu

Electricity: $ /KWh

CEPCI:
Fermentation Inputs

Ave. Volumteric Rate: g/L-hr

Titer: g/L

Yield: % of Theoretical

Turnaround Time: hours

Media Cost: $ /kg CDW

Temperature: °Celsius
DSP Assumptions

Overall DSP Yield: %

% of Total OPEX: %

% of Total CAPEX: %
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TEA Details

Financial Results

This tool represents an early stage TEA, subject to the limitations of a generic aerobic bioprocess as currently modeled. Assuming a final bioprocess conforms to this model we estimate an error up to +/- 50% consistent with other early stage TEAs based on material and energy balances.

Target Selling Price: $ /kg, OPEX: $ /kg, CAPEX: $ /kg, TCI: $ Million

NPV: $ Million, ROI: %, IRR: %

$/kg Minimum Selling Price to achieve a % Margin upon initial ramp up

Projected Cumulative Cash Flow

Chemistry

Product : , Mol. Weight: (g/mole), Theor. Yield: (g Product/g Glucose)

Conversion: C₆H₁₂O₆ + NH₃ + O₂ → CHON + H₂O + CO₂

* If NaN appears, the product as entered cannot be balanced.

Process Results

Optimal Annual Capacity: (kta)

Rate: (g/L-hr), Titer: (g/L), Fermentation Yield: (g Product/g Glucose)

Final Biomass Level: (gCDW/L), Specific Rate: (g/gCDW-hr), Fermentation Time: (hrs)

Maximal OTR: (mmoles O2/L-hr), Maximal Kla: (per sec), Maximal Cooling Rate: (kJ/hr)

DSP Yield: (g Purified Product /g Produced via Fermentation)

Overall Yield: (g Purified Product /g Glucose)